Advanced undergraduate and graduate students of Biochemistry,
Biotechnology, Physiology and related biosciences.
On completion of the course, the student has gained an
understanding of the molecular mechanisms of chemical
neurotransmission and can explain how neurotransmitters act on
their receptors and induce downstream signals and is able to
integrate this information into a physiological context. The
student has also obtained practise in critical reading and
discussing literature and communicating scientific knowledge.
Basic knowledge of biochemistry and cell and molecular biology
The topics include structure and function of ligand-gated ion
channel and G-protein coupled receptors for major
neurotransmitters, and biosynthesis and metabolism of major
neurotransmitters.The focus is on the molecular level but relevant
synaptic physiology and pharmacology will be covered as well. The
course consists of lectures, student presentations, and
Study materials and literature
Reading list covering relevant material from major textbooks
(e.g., Brady ST et al., Eds. - Basic Neurochemistry, 8
th Ed., Academic Press, 2011) and review and research
articles will be given in the beginning of and during the course
Grade (scale 1-5) is based on attendance and activity in class
(30%), presentation (30%) and the exam (40%).
Lectures, seminars (incl. own oral presentation and written
summary), and an exam.
Relations to other study units
The course provides useful background for studies of molecular
neurobiology, pharmacology and cell and molecular biology.