Students of the Master’s Programme in Translational Medicine, and students in other Master’s programmes. Maximum intake 12 students.
Spring term, period III, first or second study year. The course is arranged annually.
After the course the students will have the knowledge of basic principles in clinical proteomics and how these are applied to study complex proteomes, high throughput pathway analyses, and in the interpretation and use of relevant databases.
Active participation in lectures, PBL cases, laboratory work, assigned group tasks and a passing grade on the exam
Lectures 6 h
Seminars 3 h
PBL sessions 4 h
Laboratory work 24 h
Independent learning 33 h
Group learning 9 h
Exam 2 h
Total 81 h
Basic knowledge of biochemistry, protein structure and protein translation are required.
The course gives insights into how proteomic research is connected with clinical case studies. Students will learn the structure and function relationship of proteins by learning how to work with protein samples, e.g., by gel electrophoresis, by liquid chromatography or by mass spectrometry. Students will also learn what a proteome is, how proteins are connected to diseases, and what protein secondary modifications are. Finally, students will learn how to collect and handle clinical protein samples.
|Study materials and literature
Book chapters (Molecular Biology of the Cell, Alberts, 6th edition, Chapters 3 and 8, pp. 439–463). Additional reading includes lecture materials and review articles on lecture topics, which are provided during the course.
|Activities and teaching methods in support of learning
Lecturing, PBL sessions, hands-on learning, self-studies, e-exam, supportive writing skills
|Assessment practices and criteria
Grading scale: Pass/fail. The laboratory work and research report are obligatory.
Research director Marc Baumann, firstname.lastname@example.org