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TMED-912 Introduction to Clinical Proteomics, 3 cr 
Code TMED-912  Validity 01.01.2017 -
Name Introduction to Clinical Proteomics  Abbreviation Intro to Clinic 
Scope3 cr   
TypeAdvanced studies
TypeCourse   
  GradingGeneral scale 
  no
    Can be taken more than onceno
Unit Master's Programme in Translational Medicine 

Teachers
Name
Marc Baumann 

Description
Target group 

Students of the Master’s Programme in Translational Medicine, and students in other Master’s programmes. Maximum intake 12 students.

 
Timing 

Spring term, period III, first or second study year. The course is arranged annually.

 
Learning outcomes 

After the course the students will have the knowledge of basic principles in clinical proteomics and how these are applied to study complex proteomes, high throughput pathway analyses, and in the interpretation and use of relevant databases.

 
Completion methods 

Active participation in lectures, PBL cases, laboratory work, assigned group tasks and a passing grade on the exam

Lectures 6 h
Seminars 3 h
PBL sessions 4 h
Laboratory work 24 h
Independent learning 33 h
Group learning 9 h
Exam 2 h

Total 81 h

 
Prerequisites 

Basic knowledge of biochemistry, protein structure and protein translation are required.

 
Contents 

The course gives insights into how proteomic research is connected with clinical case studies. Students will learn the structure and function relationship of proteins by learning how to work with protein samples, e.g., by gel electrophoresis, by liquid chromatography or by mass spectrometry. Students will also learn what a proteome is, how proteins are connected to diseases, and what protein secondary modifications are. Finally, students will learn how to collect and handle clinical protein samples.

 
Study materials and literature 

Book chapters (Molecular Biology of the Cell, Alberts, 6th edition, Chapters 3 and 8, pp. 439–463). Additional reading includes lecture materials and review articles on lecture topics, which are provided during the course.

 
Activities and teaching methods in support of learning 

Lecturing, PBL sessions, hands-on learning, self-studies, e-exam, supportive writing skills

 
Assessment practices and criteria 

Grading scale: Pass/fail. The laboratory work and research report are obligatory.

 
Responsible person 

Research director Marc Baumann, marc.baumann@helsinki.fi

 


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